The gut microbiome is key in the connection between our digestive system and our brain. The signaling that occurs between these two systems is mediated by metabolites and other compounds produced by the gut microbiome. This signaling may result in a more relaxed and controlled sleep cycle. Simple Slumber™ helps support balanced signaling between the gut and the brain and promotes peaceful, sound sleep.

Good, sound sleep involves understanding how stress, diet and environmental factors affect the body’s metabolism and quality of sleep. Steps to improve sleep often include lifestyle changes in exercise and diet. One of the easiest ways to support a healthy sleep-wake cycle is to restore balance in your gut microbiome with probiotics formulated to target the proper signaling from the gut to the brain. Our signature blend has been created to release compounds and hormones to promote sound, undisturbed sleep.

When the gut lining is compromised, bacterial by-products (metabolites and bacterial toxins) can cross the barrier and cause inflammation that directly affects how you sleep. You’ll find two proprietary strains in our six-strain formula carefully chosen to work in harmony with the other strains. This formula was designed to help the body produce metabolites that promote sleep and relaxation, prevent inflammatory compounds from crossing the barrier and decrease the pathogen load. Together, these six bacteria form a stable, sustainable bacterial community and help support a healthy gut microbiome and more importantly, support sound sleep.

Here are the key strains that
differentiate our formula:

Bacillus subtilis (DE111® by Deerland)  produces bacteriocins that aid in keeping the intestines healthy and digestion normal. If the digestive system works efficiently, it’s much easier to find restful sleep. It also helps maintain healthy levels of antioxidants and metabolites that promote better sleep.

Bifidobacterium longum supports sleep and may reduce occasional anxiety. It may also help reduce the impact of acute stress on the body. By producing metabolites key to a healthy gut, it reduces oxidative stress and stimulates the sleep centers of the brain.

Lactobacillus plantarum (TBC LP-36™) Genetic analysis of this strain indicates this organism produces short chain fatty acids and GABA (a calming metabolite) from glutamate. It also produces melatonin and metabolizes fiber and other carbohydrates to produce anti-inflammatory substances.

Lactobacillus acidophilus helps reduce sleep-perturbation markers of stress and inflammation, thus, reducing circadian disruption and promoting sleep. It produces the important amino acid glycine and malate that supports the central metabolism of the gut ecosystem.

Lactobacillus casei improves sleep under psychological stress, by reducing occasional anxiety and helps stabilize a healthy gut microbiome. When blended with the other strains in this formula, it contributes to the production of serotonin, melatonin, and antioxidants.

Leuconostoc mesenteroides (TBC LM-37™) converts sugars into mannitol, a powerful free radical scavenger. Additionally, it produces a mucin-like capsule that may protect the gut lining and makes vitamin B12 which plays a role in the production of melatonin. B12 keeps nerves and blood cells healthy and helps with normal, healthy sleep.